Serena, a six-times champion in New York who is seeded 17th, will start her campaign against Polish world number 60 Magda Linette and could face Venus in the third round before a possible fourth-round showdown with Romanian top seed Halep.
Here are eight men to watch on the Roland Garros clay.
IMAGES from matches on Day 8 at the French Open
Austria's health ministry on Saturday gave the green light to two Formula One motor races on July 8 and 12 - the delayed season-openers - to be held without spectators in line with plans aimed at halting the spread of COVID-19. Austria is among countries moving ahead with easing restrictions as new coronavirus infections wane.
He made a solid start against France's Adrian Mannarino to take a 5-2 lead in the opening set but injured his wrist in the eighth game before retiring.
The two great rivals meet at Roland Garros for the first time in eight years in Friday's tie.
Images from Sunday's action in the Premier League
Andy Murray embarks on his first Grand Slam campaign as world number one with much stronger title credentials, even if he has lost five finals at Melbourne Park.
Underarm serve could be an effective weapon in halting Rafael Nadal's annual rampage on clay most just chuckled.
It was a triumphant return to the tour for Djokovic
Austrian Thiem was 6-2, 3-6, 7-5, 5-7, 4-1 up when the men's match, which had already been halted on Friday because of bad weather, was stopped.
Images from Day 2 of the 2020 US Open in New York
Indian shuttler Ajay Jayaram notched up a superb straight-game win over Estonia's Raul Must in the finals to defend his men's singles title at the Dutch Open Grand Prix in Almere, The Netherlands on Sunday.
Juan Martin del Potro's summer renaissance continued on Monday as the unseeded Argentine advanced into the US Open quarter-finals when Austrian eighth seed Dominic Thiem quit their match with an injury.
Indian tennis stars Leander Paes and Sania Mirza cruised into the mixed doubles pre-quarterfinals of the French Open along with their respective partners in Paris on Thursday. While Paes and his Swiss Partner Martina Hingis, winners of three Grand Slam titles last season, beat German-Colombian pair of Anna-Lena Groenefeld and Robert Farah 6-4 6-4 in the opening round, second seeded Sania and Ivan Dodig of Croatia eased past French duo of Mathilde Johansson and Tristan Lamasine 6-4 6-3 in their opener later in the day. However, it was curtains for another Indian Purav Raja, who, along with Ivo Karlovic of Croatia, crashed out in the opening round of the men's doubles event. The duo lost 1-6 2-6 against ninth seeded Polish-Austrian pair of Lukasz Kubot and Alexander Peya.
US Open, the final Grand Slam of the season, starts Monday, August 28, at Flushing Meadows in New York.
Jaishankar also met his Iranian counterpart H Amirabdollahian and held productive discussions on bilateral economic cooperation, Afghanistan and the joint comprehensive plan of action, also known as the Iran nuclear deal.
Grit, determination, nerves were all on show at the US Open final.
Former world number one Simona Halep stepped up her French Open preparations with a 6-4, 6-4 victory over American Coco Gauff to march into the quarter-finals of the Madrid Open on Monday while Andy Murray won on clay for the first time in five years.
Images from Day 9 at the French Open.
Images from Wednesday's action in the English Premier League.
Having dug in early on to stay with Federer, Nishikori ended up running away with the match to inflict a first straight sets defeat in the ATP Finals round-robin stages on the 20-time Grand Slam champion.
Images from Day 6 of the French Open matches played at Roland Garros in Paris on Friday.
Second seed Roger Federer powered to a 6-4, 6-3, 6-2 win over Roberto Bautista on Tuesday, charging into the quarter-finals of the US Open for the 10th time in 11 years.
The 2009 champion who will next face Roger Federer, saved two match points in the fourth set of what was arguably the best of the tournament so far.
Dominic Thiem fell in straight sets to Rafael Nadal in the 2018 French Open final but took the 12-time Roland Garros champion to four sets last June. On Sunday, the Austrian appeared to be heading towards a four-set victory before Djokovic mounted a spectacular comeback to deny him again.
Champions League winners Real Madrid outclassed Eintracht Frankfurt 2-0 on Wednesday to clinch the UEFA Super Cup for a record-equalling fifth time and kick off their season with a trophy.
While Federer and Nadal will look to reignite the flair and fight they showed to reach last year's final, 2018 could have a different script at play.
World number one Rafael Nadal set a new record of winning 50 consecutive sets on a single surface by beating Argentine Diego Schwartzman 6-3, 6-4 on Thursday to reach the Madrid Open quarter-finals.
Formula One got back on track in changed circumstances on Friday but with Mercedes bringing a familiar look to the timing sheets as six times World champion Lewis Hamilton led team mate Valtteri Bottas one-two in Austrian Grand Prix free practice. The Briton did 41 laps and lapped with a best time of one minute 04.816 seconds in a damp and overcast session, 0.356 faster than the Finn.
City did not replace Argentine striker Sergio Aguero last year when the club's all-time top scorer moved to Barcelona on a free transfer.
Raducanu stormed into the third round of the Cincinnati Open
"It's not even a dream to win here 11 times, because its impossible to think of something like this."
A dominant Rafael Nadal arrived at one career milestone on Thursday but the speed of the Spaniard's rampage through the early rounds of the French Open suggests his eyes are fixed firmly on another more significant one.
The Serena Williams show continued at the US Open as the world number one moved a step closer to a calendar Grand Slam on Wednesday, while Mardy Fish took a final Flushing Meadows bow as the curtain came down on the American's career.
Austrian Dominic Thiem beat Kevin Anderson for the first time at the seventh attempt to reach the Madrid Open final for the second successive year on Saturday.
Images from Day 7 of the 2019 French Open in Paris on Saturday.
IMAGES from Day 5 of the Australian Open in Melbourne, on Friday.
Indian tennis players enjoyed an all-win day at the US Open as three of them reached the men's doubles third round with their respective partners, while Sania Mirza entered the women's doubles pre-quarters.
Summary of sports events and persons who made news on Saturday